BDBM136570 US8865706, 9

SMILES C[C@H]1SC(N)=N[C@]2(CO[C@H](C[C@@H]12)c1cc(C)no1)c1ccc(F)cc1F

InChI Key InChIKey=HVEVDFRWOQHAPJ-CKMNQQOVSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 136570   

TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of recombinant cathepsin D (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of CatD (unknown origin) assessed as fluorescence polarization by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM136570(US8865706, 9)
Affinity DataIC50:  140nMAssay Description:Inhibition of cathepsin D (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed